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LINC00673-V4 Promotes Colorectal Cancer Cell Proliferation by Interacting With FUS and Restoring the Expression of

Wei Lu1,2,3, Jiamin Zhong4, Yunxiang Zhou5

  • 1Department of Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009 Hangzhou, Zhejiang, China.

Frontiers in Bioscience (Landmark Edition)
|July 30, 2026
PubMed
Summary

The long non-coding RNA LINC00673-V4 promotes colorectal cancer (CRC) growth by interacting with FUS, inhibiting the Hippo-YAP pathway. This finding identifies LINC00673-V4 as a potential therapeutic target for CRC.

Keywords:
Hippo signaling pathwayLINC00673-V4RNA-binding protein FUScolorectal cancer

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