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Digital Tools and Strategies for Engaging Patients in Cancer Clinical Trials
Aurora Occa1, Jerod L Stapleton2
1Department of Communication, University of Kentucky, Lexington, KY, USA.
Cancer Control : Journal of the Moffitt Cancer Center
|July 30, 2026
Summary
Digital tools enhance patient engagement in cancer clinical trials by improving recruitment and education. Evidence-based design strategies are crucial for optimizing patient understanding, trust, and decision-making in research.
Area of Science:
- Health Communication
- Behavioral Science
- Patient-Centered Design
Background:
- Digital tools are increasingly vital for patient engagement in cancer clinical trials, influencing recruitment, education, and electronic consent processes.
- The integration of these tools into clinical research workflows highlights their impact on patient perception, interpretation, and decision-making, especially under emotional and cognitive stress.
Purpose of the Study:
- To conduct a narrative mini-review of current digital tools used in cancer clinical trials.
- To identify challenges related to patient access and experience with these digital tools.
- To synthesize evidence-based design strategies for enhancing patient engagement and decision-making.
Main Methods:
- Review of current digital approaches including websites, mobile applications, social media, patient portals, e-consent platforms, and AI-driven tools.
- Synthesis of research from health communication, behavioral science, and patient-centered design.
- Analysis of challenges and evidence-based design strategies for digital patient engagement.
Main Results:
- Identified key challenges in patient access and experience with digital tools in cancer clinical trials.
- Synthesized evidence-based design strategies to support patient decision-making, reduce burdens, and build trust.
- Highlighted the importance of complementing, not replacing, human interaction through digital tools.
Conclusions:
- Future directions emphasize theory-informed, co-designed digital communication strategies for meaningful participation in cancer clinical research.
- Implementation and evaluation should assess patient understanding, decisional confidence, retention, and equity alongside enrollment metrics.
- Optimizing digital tools requires a focus on patient-centered design to support informed decision-making and engagement.
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