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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Impact of obstructive lung disease on survival in patients with rheumatoid arthritis related interstitial lung
Lee Fidler1, Omri A Arbiv2, Jolene Fisher3
1Division of Respirology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Division of Respirology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Respirology, Department of Medicine, University Health Network, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada.
Abstract:
Chronic obstructive pulmonary disease (COPD) and asthma are common comorbidities in rheumatoid arthritis related interstitial lung disease (RA-ILD), yet their impact on health outcomes is poorly understood. Using health services data from Ontario, Canada, we aimed to evaluate the effect of COPD, asthma and COPD/asthma overlap (ACO) on survival in patients with RA-ILD. Among 6470 RA-ILD patients 4437 (68.6%) had obstructive lung disease. COPD and ACO were associated with significantly increased mortality compared to RA-ILD with asthma and RA-ILD alone. These results highlight the burden and deleterious effects of COPD in patients with RA-ILD.
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