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Visual Working Memory in Older Adults With and Without Early-Onset Depression: An Ecological Momentary Assessment
Clio E Franklin1, Boyu Ren2, Jack R Kaufman3
1Department of Psychiatry and Behavioral Sciences (CEF), Johns Hopkins University School of Medicine, Baltimore, MD; Department of Psychiatry (CEF, BR, MS, REP, SLW), Mass General Brigham, Boston, MA.
Early-onset depression (ED) impacts visual working memory (VWM) in older adults, with cognitive function showing potential for improvement. This study explored VWM changes in those with and without a history of depression.
Area of Science:
- Neuroscience
- Psychology
- Gerontology
Background:
- Early-onset depression (ED) can have long-term effects on cognitive function.
- Visual working memory (VWM) is crucial for daily activities and may be affected by a history of depression.
Purpose of the Study:
- To investigate the impact of early-onset depression (ED) on visual working memory (VWM) in older adults.
- To explore differences in VWM between individuals with and without a history of depression (CON).
- To examine VWM in remitted versus non-remitted depression.
Main Methods:
- 79 participants (aged 55-79) completed lab-based neuropsychological tests.
- Ecological momentary assessments were conducted over 14 days using smartphones.
- Visual working memory (VWM) was assessed using a dot memory task, measuring response time and error distance.
Main Results:
- Participants with ED exhibited slower baseline response times compared to controls.
- The ED group showed faster decreases in response time over the study period, particularly the actively depressed subgroup.
- No significant differences were found in error distance levels or change rates between groups.
- Within-person variability in error distance decreased less in the ED group over time.
Conclusions:
- Visual working memory (VWM) may be a modifiable target for cognitive enhancement in individuals with depression.
- Cognitive functioning in older adults with a history of depression can potentially be improved.
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