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Updated: Aug 5, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Cumulative Duration of Severe Psoriasis: A Novel Cardiovascular Risk Predictor for Dermatologists

Bernadett B Huszti1, Noémi Á Galajda1, Seo-Ho Cho1,2,3,4

  • 1Department of Dermatology, Venereology and Dermatooncology, Semmelweis University, Mária u. 41, Budapest, 1085, Hungary.

Dermatology and Therapy
|July 30, 2026
PubMed

Insights

Cumulative duration of severe psoriasis (CDSP) exceeding 60.5 months is linked to increased cardiovascular disease (CVD) risk. This metric helps identify high-risk psoriasis patients early.

Area of Science:

  • Dermatology
  • Cardiology
  • Medical Diagnostics

Background:

  • Psoriasis is associated with increased cardiovascular (CV) risk.
  • A clear link between disease duration and CV risk in psoriasis patients is lacking.
  • Early identification of high CV risk in asymptomatic psoriasis patients is needed.

Purpose of the Study:

  • To investigate the relationship between moderate-to-severe psoriasis and cardiovascular disease (CVD).
  • To introduce and determine the cutoff value for cumulative duration of severe psoriasis (CDSP) as a predictor of CVD risk.

Main Methods:

  • Cross-sectional study of 98 asymptomatic patients with moderate-to-severe psoriasis.
  • Assessed CDSP using a questionnaire and determined its threshold for CVD risk using ROC analysis.
  • Utilized coronary artery calcium scoring (CACS), segment involvement score (SIS), CAD-RADS™, and intima-media thickness (IMT) for CVD assessment.

Main Results:

  • Patients with psoriasis had significantly higher CACS than controls.
  • The CDSP threshold was identified as 60.5 months.
  • Long-CDSP (over 60.5 months) was associated with significantly higher CACS, SIS, and CAD-RADS™ scores.

Conclusions:

  • Long-CDSP indicates a greater extent and severity of CVD in psoriasis patients.
  • CDSP is a novel, easily determined predictor for early identification of high CV risk in asymptomatic psoriasis patients.
Abstract

Keywords:
AtherosclerosisCardiovascular diseasesInflammationPsoriasis

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