Blood coagulation valves in normal sheep and in two mutant strains with hyperbilirubinemia

Blood coagulation values for normal sheep and lambs, using commercially available reagents for human coagulation, are reported. Of the domestic animal species for which coagulation values have been reported, the sheep most closely resembles those of humans. Factor VII deficiency has been found in some patients with Dubin Johnson syndrome. Sheep with the same defect were found to have no coagulation abnormality.