G4DARI: an intuitive graphical interface for Monte Carlo radiation dose calculation using GATE/GEANT4

GEometry ANd Tracking, version 4 (GEANT4) Dose and Radiation Interaction (G4DARI) is a GEANT4 Application for Tomographic Emission (GATE)/GEANT4 built graphical, Windows-based interface designed to facilitate Monte Carlo dose calculations in computed tomography images of patients, small animals, and phantoms. Developed to remove the programming barrier commonly associated with handling image formats and using GATE and GEANT4 coding, G4DARI integrates Oracle virtual machine (VM) VirtualBox for running the simulation environment and PuTTY for secure communication between the VM and the host system. The interface allows users to perform complete Monte Carlo dose simulations using only mouse interactions, providing a streamlined workflow for clinically relevant simulations, preclinical and research applications, and educational purposes. This manuscript describes the architecture, workflow, and features of G4DARI, from the conversion of Digital Imaging and Communications in Medicine (DICOM) images to dose determination in any region of the digital image. Furthermore, G4DARI is freely available for download, providing users with an accessible platform for running their own dosimetry simulations.