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Splenic Granulomatous Lesions Mimicking Metastases on 18 F-FDG PET/CT in a Patient With Ovarian Cancer
Na-Wa Xie1, Wen-Shan Huang2, Jiang-Kun Yu2
1Department of Nuclear Medicine, Zhuhai Clinical Medical College of Jinan University (Zhuhai People's Hospital, The Affiliated Hospital of Beijing Institute of Technology), Zhuhai, Guangdong, China.
Abstract:
A 76-year-old woman with a history of ovarian cancer underwent 18 F-FDG PET/CT due to increased CA199 levels in routine surveillance. PET/CT demonstrated multiple hypermetabolic lesions in the spleen, as well as reactive changes of hypermetabolic lymph nodes in the mediastinal and bilateral hilar region. Histopathologic examination of the splenectomy specimen confirmed granulomatous lesions, which can be easily misinterpreted as metastases.
