Related Experiment Video
Updated: Aug 5, 2026

Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein
Published on: June 30, 2019
[Analysis and reflection on pharmacological effects and novel formulation technologies of lumbrokinase from
Wen-Yu Luo1, Fei-Yan Zhao2, Jun-Feng Huang2
1State Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine,Jiangxi University of Chinese Medicine Nanchang 330004,China Key Laboratory of Modern Preparation of TCM,Ministry of Education,Jiangxi University of Chinese Medicine Nanchang 330004,China.
Abstract:
Lumbrokinase, a serine protease complex extracted from Pheretima, possesses specific fibrinolytic activity and is clinically used for thrombolytic therapy in cardiovascular and cerebrovascular diseases. Due to its low bleeding risk profile, novel formulation technologies have significantly enhanced its therapeutic efficacy in acute thrombotic diseases. This study discussed the physicochemical properties, absorption properties, pharmacological effects, formulation strategies, and existing challenges of lumbrokinase, providing a comprehensive analysis for its future application and development.
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Local Anesthetics: Pharmacokinetics
Pharmacogenomics: Identification of New Drug Targets

