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Acute Transverse Myelitis and Pulmonary Thromboembolism Following Scorpion Envenomation: A Rare Case Report
Puneet Rijhwani1, Somil Jain2, Deepak Gupta3
1Professor and Head, Department of General Medicine, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, Rajasthan, India.
Abstract:
Scorpion envenomation is common in India but rarely leads to neurovascular complications. We present a rare case of a 72-year-old male who developed acute transverse myelitis, subarachnoid hemorrhage, and pulmonary thromboembolism following a scorpion sting. The patient presented with sudden-onset paraparesis. Magnetic resonance imaging (MRI) of the spine revealed longitudinal hyperintensity from T5 to T12, suggestive of transverse myelitis, along with evidence of spinal subarachnoid hemorrhage. Computed tomography (CT) pulmonary angiography confirmed bilateral pulmonary thromboembolism. Cerebrospinal fluid analysis showed a hemorrhagic tap with elevated protein and lactate dehydrogenase (LDH), but no infectious or malignant cells. Neuromyelitis optica (NMO) and myelin oligodendrocyte glycoprotein (MOG) antibodies were negative. Nerve conduction studies showed bilateral sensorimotor axonal polyneuropathy. The patient was treated with corticosteroids and anticoagulants and showed gradual improvement. This case underscores the systemic toxicity of scorpion venom and highlights the importance of early recognition and multidisciplinary management of rare neurovascular complications.
Insights
A rare case details a 72-year-old man experiencing transverse myelitis, subarachnoid hemorrhage, and pulmonary thromboembolism after a scorpion sting. This highlights scorpion venom
Area of Science:
- Neuroscience
- Toxicology
- Internal Medicine
Background:
- Scorpion envenomation is prevalent in India, typically causing local effects.
- Neurovascular complications from scorpion stings are exceptionally rare.
Purpose of the Study:
- To report a unique case of severe neurovascular complications following a scorpion sting.
- To emphasize the systemic toxicity and diverse clinical manifestations of scorpion venom.
Main Methods:
- Case report of a 72-year-old male with paraparesis post-scorpion sting.
- Diagnostic workup included MRI spine, CT pulmonary angiography, CSF analysis, and nerve conduction studies.
- Treatment involved corticosteroids and anticoagulants.
Main Results:
- The patient presented with acute transverse myelitis, spinal subarachnoid hemorrhage, and bilateral pulmonary thromboembolism.
- Cerebrospinal fluid analysis revealed hemorrhagic tap with elevated protein and LDH.
- Negative results for Neuromyelitis optica (NMO) and Myelin Oligodendrocyte Glycoprotein (MOG) antibodies.
- Nerve conduction studies indicated a bilateral sensorimotor axonal polyneuropathy.
Conclusions:
- Scorpion venom can induce severe, multi-systemic neurovascular complications.
- Early recognition and a multidisciplinary approach are crucial for managing these rare presentations.
- This case expands the known spectrum of scorpion envenomation effects.
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