Galectin-3 Negatively Regulates miR-31 Processing in Breast Cancer Cells

Gi Soo Youn, Woo Young Lim, Yubin Kim

  • 1Department of Biomedical Science, Hallym University, Chuncheon, Gangwon State 24252, Republic of Korea; Multidisciplinary Genome Institute, Hallym University, Chuncheon, Republic of Korea.

BMB Reports
|August 3, 2026
PubMed
Summary

Galectin-3 negatively regulates microRNA-31 (miR-31) maturation in breast cancer. This study reveals Galectin-3 binds pre-miR-31, inhibiting its processing and leading to reduced tumor suppressor miR-31 levels in cancer cells.

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