Related Experiment Video
Updated: Aug 5, 2026

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 15, 2024
Postoperative Sciatic Neuropathy Following Ankle Surgery and Peripheral Nerve Blockade: A Case-Based Review
Anvinh Nguyen1, Christopher L Robinson2, Jamal Hasoon3
1Department of Anesthesiology Baylor College of Medicine.
Peripheral nerve blocks offer pain relief in foot surgery but can rarely cause nerve issues. This review details a case of persistent deficits after ankle surgery, emphasizing diagnostic challenges and management strategies for anesthesiologists.
Area of Science:
- Anesthesiology
- Neurology
- Orthopedic Surgery
Background:
- Peripheral nerve blocks are widely used for analgesia in foot and ankle surgery, offering effective pain management and reducing opioid use.
- Despite their safety profile, neurologic complications following regional anesthesia can pose diagnostic and management challenges for clinicians.
- Determining the cause of neurologic deficits is complex, involving factors like regional anesthesia, surgical procedures, tourniquet application, and individual patient risks.
Purpose of the Study:
- To present a case-based educational review of persistent neurologic deficits after peripheral nerve blocks in foot and ankle surgery.
- To highlight the diagnostic difficulties in attributing nerve injury to regional anesthesia, surgery, or other perioperative factors.
- To review key considerations for safe regional anesthesia practice, including risk factors, recognizing abnormal recovery, and management strategies.
Main Methods:
- A case report of a 72-year-old patient experiencing persistent sciatic-distribution motor and sensory deficits post-ankle surgery is presented.
- The patient received adductor canal and popliteal sciatic nerve blocks for intraoperative and postoperative analgesia.
- A review of perioperative factors, risk assessment, and diagnostic approaches for neurologic complications is integrated with the case discussion.
Main Results:
- The case illustrates the challenge of diagnosing the etiology of neurologic deficits in the context of regional anesthesia and surgery.
- Persistent motor and sensory deficits in the sciatic nerve distribution were observed postoperatively.
- The review underscores the importance of a structured approach to identify and manage potential nerve injuries.
Conclusions:
- Persistent neurologic deficits after regional anesthesia require careful diagnostic evaluation to determine causation.
- Anesthesiology trainees and clinicians should be aware of risk factors and strategies for managing neurologic complications.
- Early recognition and evidence-based management are crucial for optimizing patient outcomes following regional anesthesia for foot and ankle procedures.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...