Related Experiment Video
Updated: Aug 5, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Lasting Financial and Professional Impacts Among Survivors of Early-Onset Colorectal Cancer
Clare E Jacobson1,2, C Ann Vitous2, Samantha L Savitch1,2
1Department of Surgery, University of Michigan, Ann Arbor, Michigan.
Background:
Patients with early-onset colorectal cancer (age < 50) are vulnerable to unique psychosocial consequences given their developmental stage in life. Younger adults are often establishing their careers and families, and a cancer diagnosis can contribute to financial and professional instability. However, the lived experiences of patients with early-onset colorectal cancer have largely been underexplored.
Objective:
To characterize the financial and professional experiences of patients with early-onset colorectal cancer.
Design:
Semistructured interviews with patients with early-onset colorectal cancer.
Settings:
Multicenter study across 7 academic medical centers.
Patients:
Patients diagnosed with colon or rectal cancer before aged 50years.
Main Outcome Measures:
Thematic analysis of financial and professional impacts from early-onset colorectal cancer. Exploration of risk factors and drivers of these effects.
Results:
Participants described a range of lasting impacts related to professional and financial impacts following early-onset colorectal cancer, from minimal to severe. Financial impacts included treatment costs, indirect expenses, income loss, reduced assets, and debt. Professional impacts included physical, cognitive, psychologic challenges, and career disruptions. Certain protective factors like supportive work environments or good insurance appeared to mitigate the severity the impacts experienced.
Limitations:
Limitations include recall, negativity, and survivorship biases.
Conclusions:
Survivors of early-onset colorectal cancer face persistent financial and professional effects. Many younger adults have variable access to paid leave and public assistance programs, exacerbating the strain of early-onset colorectal cancer. Protective factors, such as a supportive workplace, access to paid time off, and flexible accommodations, must be strengthened and expanded to better care for the growing population of younger adult cancer survivors. See Video Abstract.
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