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Updated: Aug 5, 2026

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Local Solvent Ordering Drives Supramolecular Chirality Inversion

Triza Pal1, Akta Singh2, Subinoy Adhikari2

  • 1Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER), Kolkata, India.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|August 3, 2026
PubMed
Summary

Local solvent organization directly controls supramolecular chirality, reversing helical sense in L-phenylalanine perylene bisimide (L-PhePBI) assemblies. This stereomutation is driven by solvent-induced changes in molecular packing and hydrogen bonding, not bulk properties.

Keywords:
chemistrydiimidehelicityhydrogen  bondmolecular dynamicperylenesolvation  shellsolvophobicsupramolecular chemistry

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