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Sedentary Behavior and Physical Activity in Individuals With Bipolar Disorder: An Evidence Synthesis and Position
Beny Lafer1, Lucas M Neves1,2, Davy Vancampfort3
1Bipolar Disorder Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.
Bipolar Disorders
|August 3, 2026
Summary
Individuals with bipolar disorder (BD) are more sedentary and less active. Physical activity and exercise show promise for improving mental and physical health in BD, reducing mood episodes and depressive symptoms.
Area of Science:
- Mental Health Research
- Exercise Science
- Bipolar Disorder Research
Background:
- Bipolar disorder (BD) is commonly associated with high sedentary behavior and low physical activity levels.
- Physical activity and exercise offer substantial benefits for mental, brain, and heart health in individuals with BD.
Purpose of the Study:
- To synthesize evidence on the impact of sedentary behavior, physical activity, and exercise on the course of bipolar disorder.
- To evaluate effects on physical health and treatment outcomes in BD patients.
Main Methods:
- A best-evidence synthesis approach was employed.
- Searched major databases (PsycINFO, SPORTDiscus, Embase, PubMed, Web of Science) up to March 2026.
- Used search terms combining physical activity, exercise, sedentary behavior, and bipolar disorder.
Main Results:
- Individuals with BD show higher sedentary behavior and lower physical activity than the general population.
- Exercise interventions show potential to improve functioning, reduce mood episodes, and alleviate depressive symptoms in BD.
- Exercise may also reduce anxiety and improve sleep, though more data is needed.
Conclusions:
- Physical activity and exercise offer promising benefits for individuals with bipolar disorder.
- High-quality evidence is still limited, necessitating further research.
- Future research should focus on large trials, better assessment tools, and integrated care programs.
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