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Updated: Aug 5, 2026

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Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
A comparative analysis of predicted spherical refractive outcomes between two swept-source optical biometers
Samir Uprety1, Cameron McLintock2,3,4, Saran Takemura5
1Vision for Life institute, Brisbane, Queensland, Australia.
Summary
The ANTERION device provides slightly more hyperopic predicted spherical equivalent (PSEq) than the IOLMaster 700 during cataract surgery planning. These differences can impact intraocular lens (IOL) power selection in up to 25% of patients.
Area of Science:
- Ophthalmology
- Medical Devices
- Optical Coherence Tomography
Background:
- Accurate ocular biometry is crucial for successful cataract surgery and intraocular lens (IOL) power calculation.
- Anterior segment optical coherence tomography (OCT) devices are increasingly used for pre-operative measurements.
Purpose of the Study:
- To compare the predicted spherical equivalent (PSEq) generated by the ANTERION anterior segment OCT and the IOLMaster 700.
- To assess the clinical significance of differences in PSEq measurements between these two devices for cataract surgery.
Main Methods:
- Ocular biometry was performed using both ANTERION and IOLMaster 700 in patients scheduled for cataract surgery.
- IOL power and PSEq were calculated using various established IOL formulas for a specific IOL model.
- The study evaluated the mean difference in PSEq and the proportion of eyes with a clinically significant difference (>0.35 D).
Main Results:
- The ANTERION device consistently yielded a more hyperopic PSEq compared to the IOLMaster 700, with mean differences ranging from +0.11 D to +0.18 D across formulas.
- These differences were statistically significant (P < 0.05).
- While most measurements fell within the 95% limits of agreement, 15-25% of eyes exhibited a PSEq difference exceeding 0.35 D.
Conclusions:
- The ANTERION device produces a slightly more hyperopic PSEq compared to the IOLMaster 700.
- The observed discrepancies are significant enough to potentially influence intraocular lens power selection in a notable percentage of cases (up to 25%).
