Related Experiment Video

Updated: Aug 5, 2026

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

Circ_PRKCA Drove NSCLC Progression via SRSF1/HIF-1A/PKM2 Axis-Mediated Glycolytic Reprogramming

Haiting Chen1, Xingxing Jin2, Leilei Tao1

  • 1Department of Medical Oncology, Yancheng No.1 People's Hospital, Affiliated Hospital of Medical School, Nanjing University/ The Yancheng Clinical College of Xuzhou Medical University/ Yancheng Clinical Medical College of Jiangsu University, Yancheng, 224005, Jiangsu, China.

Experimental Cell Research
|August 3, 2026
PubMed
Summary

Circular RNA PRKCA (circPRKCA) promotes non-small cell lung cancer (NSCLC) growth and metastasis by stabilizing HIF-1A. This study identifies circPRKCA as a potential diagnostic biomarker and therapeutic target for NSCLC.

Keywords:
HIF-1ANSCLCPKM2SRSF1circPRKCA

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