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Updated: Aug 5, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Simply adding positive end-expiratory pressure has limited effects on oxygenation in obese dogs
Manuel Martin-Flores1, Joaquin Araos1, Taylor A Rondon1
1Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Abstract:
Positive end-expiratory pressure (PEEP) can be used to prevent atelectasis during anesthesia. We evaluated the effect of PEEP on intra- and postoperative oxygenation on obese dogs admitted for stifle surgery. Dogs received no PEEP (ZEEP; n = 10) or 7 cmH2O PEEP (n = 9) at random during general anesthesia. The partial pressure of arterial oxygen (PaO2) and its ratio to inspired fractional oxygen (PaO2:FiO2) were measured at start and end of surgery (FiO2 1.0), and 20, 120, and 240 minutes after extubation (FiO2 0.2). Cases of hypoxemia (PaO2 < 80 mmHg) were identified. There were no differences between treatment for either variable (P > 0.1 for treatment and P > 0.6 for treatment*time, for both variables). There were three cases of postoperative hypoxemia in the ZEEP treatment (P = 0.21). No significant improvement was achieved when PEEP 7 cmH2O was applied in isolation. Successful use of PEEP may require additional maneuvers.
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