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User Interface Design for AI-Based Medical Imaging: A Scoping Review
Isabela Cristina Amaro Souza1, Lilian Berton2
1Dep. of Science and Technology, Universidade Federal de São Paulo, São José dos Campos, SP, 12247-014, Brazil.
Journal of Imaging Informatics in Medicine
|August 3, 2026
Summary
This review highlights evolving graphical user interface (GUI) design for computer-aided diagnosis (CAD) systems in medical imaging. GUIs are shifting towards interactive platforms, integrating explainable AI and uncertainty visualization for better clinical adoption.
Area of Science:
- Medical Imaging and Artificial Intelligence
- Human-Computer Interaction
- Clinical Informatics
Background:
- Graphical User Interfaces (GUIs) are crucial for computer-aided diagnosis (CAD) systems in medical imaging.
- A gap exists in literature regarding GUI design and clinical workflow integration for CAD.
- Effective GUIs enhance usability, interpretability, and adoption of AI-driven medical imaging tools.
Purpose of the Study:
- To review and analyze GUI design approaches and trends in CAD systems for medical image analysis.
- To focus on classification and segmentation tasks within CAD systems.
- To examine interaction patterns, clinical applications, datasets, AI algorithms, and evaluation protocols.
Main Methods:
- A scoping review of scientific publications from 2020-2024 across five major databases.
- Used search string: "medical image" AND ("computer-aided diagnosis" OR "CADx" OR "CAD") AND "user interface".
- Included 46 studies after screening and applying inclusion/exclusion criteria.
Main Results:
- Growing trend of integrating interactive machine learning, uncertainty visualization, and explainable AI (XAI) into GUIs.
- CAD system GUIs are evolving from static displays to interactive, collaborative platforms.
- GUIs now offer tools for clinicians to understand, question, and refine AI analyses.
Conclusions:
- The design of GUIs for medical CAD systems is advancing towards more interactive and informative interfaces.
- There is a need for standardized usability and human-computer interaction metrics for evaluating these systems.
- Future research should focus on developing and validating these standardized evaluation metrics.