Related Experiment Video

Updated: Aug 5, 2026

Isolating Myofibrils from Skeletal Muscle Biopsies and Determining Contractile Function with a Nano-Newton Resolution Force Transducer
07:55

Isolating Myofibrils from Skeletal Muscle Biopsies and Determining Contractile Function with a Nano-Newton Resolution Force Transducer

Published on: May 7, 2020

Determining Proximities of Sarcomeric Proteins in Living Skeletal Muscle Cells Using FRET Imaging

Jushuo Wang1, Yingli Fan1, Vasundhara Muthu2

  • 1Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York, USA.

Cytoskeleton (Hoboken, N.J.)
|August 4, 2026
PubMed
Summary

This study used fluorescence resonance energy transfer (FRET) to map protein interactions within sarcomeres of chicken skeletal muscle cells. Researchers identified new actin-binding proteins and observed structural changes during Z-band formation.

Keywords:
FRET (fluorescence resonance energy transfer)FRETsomemuscle myosin IImyofibrillogenesisnascent myofibrilsnonmuscle myosin II

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