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Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica
Published on: October 28, 2022
Cutting for Stone: A Case Report of Isolated Pleural Silicosis in an Engineered Stone Fabrication Worker
Matthew Federbush1, Alain Borczuk2,3, Arunabh Talwar4,5,6
1Division of Pulmonary, Critical Care, and Sleep Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY.
Abstract:
Silicosis typically presents with parenchymal lung disease in workers exposed to silica. We present a rare case of isolated pleural and lymph node silicosis without parenchymal involvement in a stone fabrication worker. A 49-year-old man with extensive occupational exposure to stone materials, including engineered stone without consistent use of personal protective equipment, was found to have mediastinal and hilar lymphadenopathy. Initial bronchoscopic and radiology evaluations were nondiagnostic. Video-assisted thoracoscopic surgery revealed pleural nodules, and pathologic examination demonstrated silicotic changes in both pleura and lymph nodes but without parenchymal involvement. This case demonstrates an unusual presentation of silicosis confined to the pleura and lymph nodes, highlighting the importance of thorough evaluation of thoracic pathology in workers with silica exposure. It adds to growing evidence regarding health risks in the engineered stone fabrication industry and emphasizes the need for improved occupational safety measures and medical surveillance.
