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Memory training through Chinese classics recitation for individuals with subjective cognitive decline: study protocol
Tz-Syuan Su1, Kuan-Pin Su2,3,4, Po-Ren Hsueh4,5
1School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Frontiers in Aging Neuroscience
|August 4, 2026
Summary
This pilot study investigates Chinese Classics recitation for subjective cognitive decline (SCD). The research assesses feasibility, acceptability, and potential biomarkers for early dementia intervention.
Area of Science:
- Neuroscience
- Gerontology
- Cognitive Psychology
Background:
- Subjective cognitive decline (SCD) is a preclinical stage linked to increased dementia risk.
- Effective interventions for SCD are lacking, highlighting the need for early strategies.
- Cognitive training shows promise, but requires integrated multimodal assessments for mechanism elucidation.
Purpose of the Study:
- To evaluate the feasibility and acceptability of a Chinese Classics recitation program for individuals with SCD.
- To estimate effect sizes for future definitive trials on cognitive decline interventions.
- To generate hypotheses on the link between recitation practice and clinical biomarkers in SCD.
Main Methods:
- A randomized, assessor-blinded, controlled pilot study involving 60 individuals with SCD.
- A six-month structured recitation training program for the intervention group.
- Multimodal assessments including neuropsychological tests, fMRI, EEG, blood biomarkers, and gut microbiota analysis.
Main Results:
- This section is not available in the provided abstract.
Conclusions:
- The study protocol outlines a pilot trial to assess Chinese Classics recitation for SCD.
- Findings aim to offer mechanistic insights into non-pharmacological interventions for cognitive decline.
- The research seeks to address the underrepresentation of Asian populations in neuroscience studies.
