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Updated: Aug 5, 2026

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Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
Case Report: Intestinal mycobacterium abscessus infection in a child
Linlin Zhang1, Dixi Huang2, Jie Song1
1Department of Pediatrics, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China.
Frontiers in Pediatrics
|August 4, 2026
Summary
Metagenomic sequencing rapidly diagnosed a rare pediatric Mycobacterium abscessus infection. An individualized treatment plan combining Imipenem, Azithromycin, and Linezolid achieved a successful clinical outcome, offering insights for future NTM infection management.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Genomic Medicine
Background:
- Mycobacterium abscessus infections pose diagnostic and therapeutic challenges, particularly in extrapulmonary pediatric cases.
- Limited clinical experience and treatment guidelines complicate management of these rare infections.
- Extrapulmonary non-tuberculous mycobacterial (NTM) infections in children require novel diagnostic and therapeutic strategies.
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