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Updated: Aug 5, 2026

In vitro Measurements of Tracheal Constriction Using Mice
10:20

In vitro Measurements of Tracheal Constriction Using Mice

Published on: June 25, 2012

Airway smooth muscle in asthma: insights from a transcriptomic meta-analysis

Saptarshi Roy1,2, Rahul Shubhra Mandal3,2, Sunil Kurian4

  • 1Department of Pathology and Laboratory Medicine, Thoracic Medicine and Surgery, Center for Inflammation and Lung Research, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.

ERJ Open Research
|August 4, 2026
PubMed
Summary

This study analyzed airway smooth muscle cell transcriptomes from asthma patients, identifying 150 dysregulated genes and key pathways like IL-4/IL-13 signaling. These findings offer insights into asthma mechanisms and potential therapeutic targets.

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