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Functional consequences of post-COVID-19 syndrome: Evidence from Qatar, 2022
Nada Adli1, Nagah Selim2,3
1Department of Preventive Medicine, Hamad Medical Corporation (HMC), Doha, Qatar.
Qatar Medical Journal
|August 4, 2026
Summary
Post-COVID-19 syndrome (PCS) significantly reduces physical activity and causes severe fatigue and dyspnea in adults. These symptoms are interrelated and require multidisciplinary rehabilitation for functional recovery.
Area of Science:
- Cardiology
- Pulmonology
- Rehabilitation Medicine
Background:
- Post-COVID-19 syndrome (PCS) affects individuals after acute infection, impairing cardiovascular and pulmonary function.
- Physically active adults are particularly susceptible to functional decline due to PCS.
Purpose of the Study:
- To evaluate the severity of physical dysfunction in post-COVID-19 syndrome patients in Qatar during 2022.
- To identify key symptoms and their interrelationships in PCS.
Main Methods:
- An analytic cross-sectional study involved 368 adults with confirmed COVID-19.
- Structured telephone interviews assessed physical activity, fatigue, and dyspnea using WHO PCS criteria.
- 159 participants were identified as having PCS.
Main Results:
- PCS patients showed reduced moderate (13.2%) and vigorous (5.7%) physical activity.
- Severe fatigue (45.9%) and dyspnea (37.8%) were highly prevalent and interrelated.
- Severe dyspnea and fatigue were independently associated with each other (ORs > 3).
Conclusions:
- Fatigue and dyspnea are core, interconnected symptoms of PCS, independent of other factors.
- Routine screening and multidisciplinary rehabilitation are crucial for managing PCS-related functional impairment.
- Further longitudinal studies are needed to understand PCS progression and mechanisms.
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