Glioblastoma beyond the Brain: A Case Series Demonstrating Systemic Metastatic Potential
Nidal Salim1,2, Kristina Tumanova1, Ilya Loyko1
1European Medical Center, Institute of Oncology, Moscow, Russia.
Case Reports in Oncology
|August 4, 2026
Summary
Extracranial metastasis in glioblastoma (GBM) is rare but may increase with longer survival. This case series highlights distinct GBM dissemination patterns and molecular factors influencing metastatic potential in IDH-wild-type GBM.
Area of Science:
- Neuro-oncology
- Oncology
- Pathology
Background:
- Glioblastoma (GBM) is an aggressive primary brain tumor with a low incidence of extracranial metastasis (<2%).
- Increased patient survival and advanced diagnostic tools may lead to more frequent detection of extracranial GBM dissemination.
- Understanding the mechanisms and patterns of GBM metastasis is crucial for improving patient outcomes.
