Related Experiment Video
Updated: Aug 11, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
Published on: May 12, 2023
Beyond zero-dose: routine immunization retention gaps in the Dominican Republic, 2019-2025
Manuel Colomé-Hidalgo1, José Brea2
1Universidad Autónoma de Santo Domingo (UASD), Santo Domingo, Dominican Republic.
None:
We assessed routine immunization performance in the Dominican Republic during the mid-term monitoring period of the Immunization Agenda 2030 (IA2030). Using IA2030 dashboard data for 2019-2024 and updated 2025 WUENIC and WHO/UNICEF HPV estimates, we analyzed national coverage, zero-dose and under-vaccinated children, DTP1-to-DTP3 dropout, antigen-specific coverage through 2025, and subnational inequality through 2024. The Breadth of Protection Index increased from 77.92% in 2019 to 85.62% in 2025; the 2025 value was calculated according to the WHO definition. Zero-dose children decreased from 8262 to 5839, below the expected 2025 trajectory of 6009. Under-vaccinated children increased from 14,459 to 19,463, while the dropout rate reached 10.3%. Completed HPV vaccination coverage among girls increased from 6% to 56% but remained the lowest selected indicator. Post-pandemic recovery was uneven, with persistent retention gaps and subnational inequities requiring targeted action.
Related Concept Videos
Vaccinations
Smallpox
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Drug Accumulation During Multiple Dosing: Repetitive IV Injections
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Vaccines

