[Synchronous Follicular Lymphoma and Lung Adenocarcinoma-A Case Report]
Masahiro Manabe1, Yoshiaki Matsuura, Daisuke Aohara
1Dept. of Hematology, Osaka General Hospital of West Japan Railway Company.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|August 4, 2026
Summary
This case study highlights a rare instance of synchronous follicular lymphoma and lung adenocarcinoma successfully treated with chemotherapy, surgery, and targeted therapy. The patient achieved over a year of remission, demonstrating effective multimodal management for complex cancers.
Area of Science:
- Oncology
- Hematology
- Thoracic Surgery
Background:
- Multiple synchronous malignancies, involving both hematological neoplasms and solid tumors, present a rare and complex clinical challenge.
- Effective management requires a multidisciplinary approach, integrating expertise from various medical specialties.
Purpose of the Study:
- To present a case of successful treatment for a patient with synchronous follicular lymphoma and lung adenocarcinoma.
- To emphasize the importance of multidisciplinary collaboration in managing rare complex cancer presentations.
Main Methods:
- A 67-year-old male patient received one cycle of chemotherapy (obinutuzumab and bendamustine) for follicular lymphoma and lung adenocarcinoma.
- The patient underwent lower lobectomy for lung adenocarcinoma, followed by adjuvant osimertinib therapy.
Main Results:
- The patient achieved no evidence of recurrence for both follicular lymphoma and lung adenocarcinoma for over one year post-surgery.
- Successful management was achieved through a combination of chemotherapy, surgical resection, and targeted therapy.
Conclusions:
- Multimodal treatment strategies can be effective in managing patients with synchronous hematological and solid tumors.
- Consultations across multiple medical departments are crucial for optimizing treatment plans and improving outcomes in rare complex oncological cases.