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Updated: Aug 11, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Management of acute kidney injury in critical illness
Abstract:
Acute kidney injury (AKI) is a common syndrome in critically ill patients, carrying significant implications for morbidity and mortality. The etiology and severity of AKI vary, requiring a management approach that focuses on prevention, treatment of the underlying cause, and supportive care, often involving renal replacement therapy. Numerous strategies have been proposed for preventing and treating AKI. This narrative review aims to provide a concise summary of the clinical management of AKI in critically ill patients tailored to clinicians working in the perioperative setting.
Insights
Acute kidney injury (AKI) is a critical condition in sick patients. This review summarizes AKI management, focusing on prevention and treatment for perioperative clinicians.
Area of Science:
- Nephrology
- Critical Care Medicine
Background:
- Acute kidney injury (AKI) is a frequent complication in critically ill patients.
- AKI significantly increases patient morbidity and mortality.
- Management requires addressing diverse etiologies and severity.
Purpose of the Study:
- To summarize the clinical management of AKI in critically ill patients.
- To provide guidance for clinicians in the perioperative setting.
- To focus on prevention, cause treatment, and supportive care.
Main Methods:
- This is a narrative review.
- Literature search on AKI management strategies.
- Focus on perioperative clinical practice.
Main Results:
- AKI management is multifaceted, involving prevention and treatment.
- Supportive care, including renal replacement therapy, is often necessary.
- Tailored approaches are essential due to varying AKI causes and severity.
Conclusions:
- Effective AKI management is crucial for critically ill patients.
- Perioperative clinicians need concise guidance on AKI care.
- A comprehensive strategy encompassing prevention, treatment, and support improves outcomes.
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