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[EXTRAMEDULLARY HEMATOPOIESIS PRESENTING AS A RENAL MASS DURING TREATMENT OF CASTLEMAN DISEASE : A CASE REPORT]
Iori Matsuda1, Santa Sugihara1, Shingo Kitora1
1The Department of Urology, Kurashiki Central Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|August 5, 2026
Summary
A renal mass in a Castleman disease patient was initially suspected to be cancer. A biopsy revealed extramedullary hematopoiesis, leading to observation instead of surgery.
Area of Science:
- Nephrology
- Oncology
- Pathology
Background:
- A 66-year-old male patient with Castleman disease presented with a growing renal mass detected via CT scan.
- Initial imaging (contrast-enhanced CT and MRI) suggested renal cell carcinoma, indicating potential surgical intervention.
Purpose of the Study:
- To differentiate between renal cell carcinoma and other potential causes of a renal mass in a Castleman disease patient.
- To establish a definitive diagnosis before surgical resection.
Main Methods:
- Ultrasound-guided percutaneous needle biopsy was performed for histopathological examination.
- Imaging studies including computed tomography (CT) and magnetic resonance imaging (MRI) were utilized for diagnostic evaluation.
Main Results:
- The renal mass was diagnosed as extramedullary hematopoiesis.
- Surgical resection was avoided due to the biopsy findings.
Conclusions:
- Histopathological confirmation via biopsy is crucial for accurate diagnosis of renal masses in patients with Castleman disease.
- Extramedullary hematopoiesis should be considered in the differential diagnosis of renal masses in this patient population.
- Observation without intervention is a viable management strategy for non-malignant renal lesions such as extramedullary hematopoiesis.
