Congenital Clubfoot Prevalence and Folic Acid Supplementation - Five Counties, Shanxi Province, China, 2003-2024

Lirong Nie1,2, Yuwei Wu1,2, Lingzhang Wang1,2

  • 1Institute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, School of Public Health, Peking University, Beijing, China.

China CDC Weekly
|August 5, 2026
PubMed

Insights

Congenital clubfoot prevalence is rising in China, particularly isolated cases since 2012. Non-isolated cases continue to decrease, indicating distinct trends for clubfoot subtypes.

Area of Science:

  • Pediatric Orthopedics
  • Public Health Surveillance
  • Birth Defect Epidemiology

Background:

  • Congenital clubfoot is a frequent musculoskeletal birth defect with variable prevalence.
  • Recent data indicate an increasing trend in congenital clubfoot incidence among newborns in China.

Purpose of the Study:

  • To analyze temporal trends of congenital clubfoot subtypes in China.
  • To investigate distinct epidemiological patterns between isolated and non-isolated congenital clubfoot.

Main Methods:

  • Retrospective analysis of congenital clubfoot case data.
  • Statistical trend analysis of isolated versus non-isolated congenital clubfoot incidence.

Main Results:

  • A significant increasing trend observed in isolated congenital clubfoot cases post-2012.
  • A continued declining trend noted for non-isolated congenital clubfoot cases.
  • Distinct temporal patterns identified between congenital clubfoot subtypes.

Conclusions:

  • The study highlights diverging trends in isolated and non-isolated congenital clubfoot.
  • Ongoing surveillance is crucial for monitoring clubfoot subtype patterns.
  • Further research is needed to identify factors driving the rise in isolated congenital clubfoot.
Abstract