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Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Predicting comorbidities in psoriasis using TCM constitution and multimodal data: a prospective cohort study protocol
Jing Hu1, Di Long1, Junchen Chen2
1The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Frontiers in Medicine
|August 5, 2026
Summary
This study investigates how Traditional Chinese Medicine (TCM) constitution types predict psoriasis comorbidities and treatment responses. Findings aim to enhance personalized medicine for psoriasis patients by integrating TCM with clinical data.
Area of Science:
- Integrative medicine
- Dermatology
- Genetics and genomics
Background:
- Psoriasis is a chronic inflammatory skin disease with unpredictable treatment responses and comorbidities.
- Individual variability in treatment outcomes necessitates novel predictive approaches.
- Traditional Chinese Medicine (TCM) constitution theory offers a potential framework to explain patient variability, but lacks prospective validation.
Purpose of the Study:
- To evaluate the predictive value of TCM constitution types and multimodal clinical data for comorbidity risk in psoriasis patients.
- To explore the association between TCM constitution and systemic treatment effectiveness and adverse events.
- To develop integrated predictive models for personalized psoriasis management.
Main Methods:
- A multicenter, prospective, observational cohort study involving 1000 adult psoriasis patients initiating systemic therapy.
- Data collection over 52 weeks includes TCM constitution types, syndrome patterns, and multimodal clinical data.
- Monitoring of comorbidity progression, treatment effectiveness, and adverse events.
Main Results:
- This section is to be filled once the study is completed and results are available.
Conclusions:
- This section is to be filled once the study is completed and results are available.