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Updated: Aug 6, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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A Practical and Scalable-Oriented Enantioselective Synthesis of (S)‑Autumnaline

Alessandro Brusa1, Matteo Bottiglieri2, Carola Tomassi1

  • 1Department of Physical and Chemical Sciences, Consorzio C.I.N.M.P.I.S., INSTM RU, Università degli Studi dell'Aquila, L'Aquila 67100, Italy.

Organic Process Research & Development
|August 5, 2026
PubMed

Keywords:
Bischler−Napieralski cyclizationasymmetric synthesiscircular dichroismisoquinoline alkaloids

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