Related Experiment Video
Updated: Aug 7, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Reducing Emergency Department Observation Time for Patients with Low-Risk Anaphylaxis
Stephanie Schroter1,2, Susan Laubach2,3, Mario Bialostozky1,2
1Division of Emergency Medicine, Rady Children's Hospital San Diego, San Diego, California.
Pediatric emergency departments can safely reduce observation time for low-risk anaphylaxis patients from 4 hours to under 3 hours. This quality improvement initiative decreased observation by 79 minutes without increasing return visits, aligning with updated guidelines.
Area of Science:
- Emergency Medicine
- Allergy and Immunology
- Quality Improvement Science
Background:
- Historically, anaphylaxis patients require 4-hour observation post-epinephrine to monitor for biphasic reactions.
- Updated 2020 guidelines suggest 1-hour observation for low-risk patients.
- Pediatric emergency departments face challenges in implementing shorter observation periods.
Purpose of the Study:
- To decrease pediatric emergency department observation time for low-risk anaphylaxis from 240 to 120 minutes within 9 months.
- To implement updated anaphylaxis guidelines into clinical practice.
- To assess the impact of reduced observation time on patient safety and return visits.
Main Methods:
- A multidisciplinary team identified barriers using a fishbone diagram.
- Interventions included education, EMR optimization, and feedback mechanisms.
- Statistical process control analyzed changes in observation time and return visits.
Main Results:
- Observation time for low-risk anaphylaxis decreased by 34% (79 minutes) in 5 months, sustained for 7 months.
- No change in observation time for high-risk patients.
- No missed biphasic anaphylactic reactions occurred during the intervention period.
Conclusions:
- Successfully reduced emergency department observation time for low-risk anaphylaxis.
- Achieved significant time reduction without compromising patient safety.
- Demonstrated feasibility of implementing guideline changes in a pediatric ED setting.
Related Concept Videos
Allergic Reactions: Anaphylaxis
Allergic Reactions
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and anaphylaxis:...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Desensitization and Tachyphylaxis
Several...
Cardiac Catheterization IV: Nursing Management

