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Surgery on Patients Taking Glucagon-Like Peptide-1 Receptor Agonists
Claire B Rosen1, Denise W Gee1
1Division of GI Surgery, Department of Surgery, Massachusetts General Brigham, Boston, MA, USA.
None:
This article begins by providing historical insight into the discovery, development, and use of glucagon-like peptide-1 receptor (GLP-1R) agonist medications in the treatment of type 2 diabetes and obesity. Next, the mechanism of action and impacts of GLP-1R agonists are discussed, along with an overview of the Food and Drug Administration-approved GLP-1R agonists currently on the market. Comparison in effects on weight loss of the available GLP-1R agonists is briefly discussed, along with its use in the context of bariatric surgery. Finally, perioperative considerations for surgical patients using GLP-1R agonists are reviewed along with suggested recommendations.
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