Related Experiment Video

Updated: Aug 7, 2026

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

Nanotechnology-Enabled Targeted Protein Degradation: Strategies, Opportunities, and Challenges

Haoran Zhu1, Yijun Zhang1, Yuhua Ning1

  • 1The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, the Key Laboratory of Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.

Small Methods
|August 6, 2026
PubMed
Summary

Targeted protein degradation (TPD) agents face delivery challenges. Nanotechnology integration (nano-TPD) overcomes these limitations, enabling new therapies for previously undruggable targets.

Keywords:
drug deliverynanocarriersprecision therapytargeted protein degradation

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