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Published on: March 25, 2022
Case Report: Hepatic sinusoidal obstruction syndrome caused by Gynura segetum
Bochen Xiang1, Qiang Liu2, Xiangcheng Dai1,2
1Department of Infectious Diseases, Yichang Central People's Hospital, The First College of Clinical Medical Science, China Three Gorges University, Yichang, China.
Insights
Hepatic sinusoidal obstruction syndrome (HSOS), a liver vascular disease, is increasingly diagnosed. This case highlights HSOS caused by ingesting Gynura segetum, emphasizing diagnostic challenges.
Area of Science:
- Hepatology
- Vascular Biology
- Toxicology
Background:
- Hepatic sinusoidal obstruction syndrome (HSOS) is a serious hepatic vascular disease.
- It results from damage to liver sinusoidal endothelial cells.
- HSOS incidence is rising, yet diagnosis is often delayed due to non-specific symptoms.
Abstract:
Hepatic sinusoidal obstruction syndrome (HSOS) is a hepatic vascular disease initiated by injury to hepatic sinusoidal endothelial cells. Its main clinical manifestations include hepatomegaly, elevated bilirubin, ascites and weight gain. The incidence of HSOS has been increasing year by year. Nevertheless, due to its non-specific clinical manifestations, limited effective diagnostic methods and imperfect relevant diagnostic criteria, it is highly likely to be misdiagnosed as other liver diseases. This study reports a case of HSOS induced by ingestion of Gynura segetum.
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