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Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma
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Towards a personalized perspective on gliomas: an epigenetic-immuno-inflammatory aging framework

Olga Vershinina1,2, Victoria Turubanova3,4, Claudio Franceschi2

  • 1Research Center in Artificial Intelligence, Institute of Information Technologies, Mathematics and Mechanics, Lobachevsky State University, Nizhny Novgorod, Russia.

Frontiers in Immunology
|August 6, 2026
PubMed
Summary

High-grade gliomas share molecular mechanisms with aging. Genes predicting glioma prognosis are also linked to aging, with similar expression changes during both processes, suggesting overlapping pathways.

Keywords:
age accelerationagingepigenetic clocksgliomainflammaging

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