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Transient Bilateral Fixed Dilated Pupils Following Papaverine Use During Intracranial Microvascular Decompression: A
Shajahan Idayathulla1, Shoaib Nawaz2, Nissar Shaikh1
1Surgical Intensive Care Unit, Hamad General Hospital, Doha, QAT.
Cureus
|August 6, 2026
Summary
Papaverine hydrochloride, used for cerebral vasospasm during neurosurgery, can cause temporary fixed dilated pupils. This rare side effect mimics serious neurological injury, necessitating careful consideration by medical teams.
Area of Science:
- Neurosurgery
- Anesthesiology
- Pharmacology
Background:
- Fixed dilated pupils post-neurosurgery often indicate severe brain injury or herniation.
- Pharmacological causes, though rare, must be considered in pupillary changes.