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Updated: Aug 7, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Endoscopic mitral valve replacement in extensive mitral annular calcification with a posterior pericardial patch
Carolina Orlandi1, Ghazi Elshafie2, Joseph Zacharias2
1Biomedical and Neuromotor Sciences Department (DIBINEM), University of Bologna, Italy
This case study highlights successful endoscopic mitral valve replacement in an elderly patient with severe mitral annular calcification. The minimally invasive approach effectively managed mitral regurgitation, demonstrating a viable surgical option.
Area of Science:
- Cardiovascular Surgery
- Medical Devices
- Minimally Invasive Procedures
Background:
- Extensive mitral annular calcification (MAC) poses significant challenges in mitral valve surgery.
- MAC is linked to increased operative risks, including atrioventricular disruption and prosthetic valve complications.
- Management strategies for severe mitral regurgitation with MAC are debated, even for transcatheter interventions.
Purpose of the Study:
- To present a case of severe symptomatic mitral regurgitation in a patient with extensive MAC.
- To describe the successful application of endoscopic mitral valve replacement in this challenging scenario.
Main Methods:
- The patient underwent endoscopic mitral valve replacement via right minithoracotomy with femoro-femoral cardiopulmonary bypass.
- An endoaortic balloon was used for cardiac arrest with cardioplegia.
- A bioprosthetic mitral valve was implanted, reinforced with a posterior skirt technique to mitigate paravalvular leak risk.
Main Results:
- The procedure successfully addressed severe mitral regurgitation.
- Postoperative echocardiography confirmed a well-functioning prosthetic valve and preserved left ventricular function.
- Only a trivial paravalvular leak was detected, indicating a successful outcome.
Conclusions:
- Endoscopic mitral valve replacement is a feasible and effective option for patients with extensive MAC unsuitable for transcatheter procedures.
- The posterior skirt technique can enhance prosthetic valve stability and reduce paravalvular leakage.
- Minimally invasive approaches can overcome technical challenges posed by severe MAC.
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