Empowering Movement: A Human-in-the-Loop Proportional Controller for Assisted Elbow Flexion in Brachial Plexus Injury
Sandesh G Bhat1, Alexander Y Shin2, Kenton R Kaufman1
1Motion Analysis Laboratory, Department of Orthopedic Surgery, Mayo Clinic, 200 First St. SW, Rochester, MN 55902, United States.
Military Medicine
|August 6, 2026
Summary
Neural network regression enables proportional control for powered elbow orthoses, improving human-machine connection in brachial plexus injury patients. This technology is field-deployable, with models training quickly on standard computers.
Area of Science:
- Biomedical Engineering
- Rehabilitation Technology
- Neuroprosthetics
Background:
- Powered orthotic devices offer potential but face adoption barriers due to simple control systems.
- Current controllers (e.g., bang-bang) limit nuanced interaction with the user.
- Developing proportional controllers is challenging due to patient-specific injury and recovery variations.
Purpose of the Study:
- To evaluate the feasibility of a proportional controller for a powered myoelectric elbow orthosis (PMEO).
- To investigate the use of neural network regression (NNR) for real-time EMG-to-torque control.
- To assess the potential for field deployment of NNR-based control in clinical settings.
Main Methods:
- Collected elbow flexion torque and EMG data from 31 brachial plexus injury (BPI) participants.
- Utilized a 2-layer neural network regression model with Tanh activation and cross-validation.
- Trained NNR models on participant-specific EMG features (e.g., RMS, variance) to predict elbow torque.
Main Results:
- NNR models trained on standard computers within clinically relevant times (median 82 seconds).
- Low prediction latency (median 7 milliseconds) achieved for real-time control.
- Achieved a median test Root Mean Squared Error (RMSE) of 0.39 Nm, with some models showing R2 > 0.7.
Conclusions:
- NNR is a viable method for creating proportional controllers for PMEOs.
- The training process is efficient and can be performed in a clinical setting.
- This approach enhances the human-machine connection for individuals with BPI, paving the way for field-deployable solutions.
Related Concept Videos
Muscles that Move the Forearm
The muscles that move the forearms can be divided into four groups: forearm flexors, forearm extensors, forearm pronators, and forearm supinators. The flexors and extensors act on the elbow joint, while the pronators and supinators act on the radioulnar joints.
Forearm Flexors
The biceps brachii, brachialis, and brachioradialis are forearm flexors. The biceps brachii is made up of two heads. Its long head originates at the supraglenoid tubercle of the scapula, whereas that of the short head is...
Forearm Flexors
The biceps brachii, brachialis, and brachioradialis are forearm flexors. The biceps brachii is made up of two heads. Its long head originates at the supraglenoid tubercle of the scapula, whereas that of the short head is...
Bones of the Upper Limb: Ulna
The ulna and radius are parallel bones of the antebrachium or the forearm. The ulna lies medially and consists of a bony tip called the olecranon process at its proximal end. This hook-like projection articulates with the olecranon fossa of the humerus and forms the "hinged" ulnohumeral part of the elbow joint. This joint facilitates forearm extension and flexion while preventing its hyperextension. Similarly, the coronoid process, another bony projection on the proximal/anterior side of the...
Muscle Coordination and Action
Muscle coordination is a complex and finely tuned process essential for smooth and purposeful movements like flexion, extension, adduction, abduction, and rotation. The human body orchestrates the actions of various muscles working in concert, each with a specific role. Four functional types describe how muscles work together: agonist, antagonist, synergist, and fixator.
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement.
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement.


