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Infective endocarditis following transcatheter valvular interventions (transcatheter aortic valve implantation and

Edyta Płońska-Gościniak1, Wojciech Wojakowski2, Marek Deja3

  • 1Department of Cardiology, Pomeranian Medical University, Szczecin, Poland. edytaplonska@life.pl.

Kardiologia Polska
|August 6, 2026
PubMed

Insights

Infective endocarditis (IE) after transcatheter valve procedures is rare but serious. Early diagnosis with advanced imaging and multidisciplinary care are key to improving outcomes for this challenging complication.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Devices

Background:

  • Infective endocarditis (IE) is a rare but life-threatening complication following transcatheter valvular interventions.
  • The incidence of device-related IE is expected to rise with expanding indications for structural interventions.
  • Transcatheter aortic valve implantation (TAVI)-related IE has an incidence of 0.3-2.0 per 100 person-years, with high mortality.

Purpose of the Study:

  • To summarize contemporary evidence on the epidemiology, presentation, diagnosis, treatment, and prevention of transcatheter valve-related IE.
  • To provide expert opinion on managing this complication.
  • To highlight challenges in diagnosis and treatment.

Main Methods:

  • Review of contemporary evidence on transcatheter valve-related IE.
  • Expert opinion developed by the Association of Valvular Heart Disease and the Association of Cardiovascular Intervention of the Polish Cardiac Society.
  • Discussion of diagnostic modalities including echocardiography, cardiac CT, and PET.

Main Results:

  • IE after TAVI and transcatheter edge-to-edge repair (TEER) is associated with high mortality.
  • Clinical presentation is often atypical, leading to delayed diagnosis.
  • Multimodality imaging significantly improves diagnostic accuracy, especially for perivalvular complications.

Conclusions:

  • Management requires prolonged antibiotic therapy and consideration of surgical intervention in severe cases.
  • Preventive measures like strict asepsis and antibiotic prophylaxis are crucial.
  • IE after transcatheter interventions necessitates high clinical vigilance, multidisciplinary management, and individualized strategies.

Keywords:
infective endocarditistranscatheter aortic valve implantationtranscatheter edge-to-edge repair

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