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Fluid-Structure Interaction Analysis of Human Eye with Descemet Membrane Detachment
Ammar I Alsabery1, Muneer A Ismael2,3, Zehba Raizah4
1Refrigeration & Air-Conditioning Technical Engineering Department, College of Technical Engineering, The Islamic University, Najaf, Iraq. ammar_e_2011@yahoo.com.
Annals of Biomedical Engineering
|August 6, 2026
Summary
This study models detached Descemet membrane (DM) in the human eye, revealing cornea type impacts stress but not thermal displacement. Iris shrinkage significantly boosts convective heat transfer.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Fluid Dynamics
Background:
- Detachment of Descemet membrane (DM) is a corneal defect.
- Previous studies often overlook the complex interplay between intraocular fluid flow and delicate ocular structures like the DM.
Purpose of the Study:
- To simulate detached DM as a flexible membrane.
- To explore convection within the anterior chamber (AC).
- To evaluate cornea transplantation processes.
Main Methods:
- Numerical simulation of fluid-structure interaction (FSI) in an AC geometry.
- Analysis of varying DM elasticity modulus (E) from 10^8 to 10^11 Pa.
- Simulation of thermal therapy by varying Rayleigh number (10^3 to 10^6) and temperature difference (0.25 to 250 K).
Main Results:
- Cornea type influences stress on the DM but not thermal characteristics or AC displacement.
- Iris shrinkage increases convective thermal characteristics by approximately 78%.
- Increasing thermal therapy (ΔT from 2.5 to 25 K) enhances heat transfer by 47.6%.
Conclusions:
- The mechanical properties of the cornea significantly influence stress distribution in detached DM.
- Thermal conditions and iris geometry play crucial roles in modulating heat transfer within the AC.
- Findings offer insights into optimizing cornea transplantation and thermal therapies.
