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Updated: Aug 8, 2026

Comparative in vivo Study of gp96 Adjuvanticity in the Frog Xenopus laevis
Published on: September 16, 2010
How frog proteins soak up toxins
1Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Abstract:
In this issue of Structure, Zakrzewska et al.1 reveal the molecular principles underlying how a wide variety of natural and synthetic paralytic shellfish toxins (PSTs) bind to saxiphilins, naturally occurring proteins found in certain frog species, providing crucial insights into PST interactions with biological targets more broadly.
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