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DTaP-IPV Vaccination-Induced Granuloma Diagnosed With Multi-Virus/Microbial Real-Time PCR
Hiroshi Hayashi1, Yuto Otsubo2, Kentaro Matsuoka3
1Department of Hematology/Oncology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Pediatric Dermatology
|August 6, 2026
Summary
Vaccination-induced granuloma diagnosis was advanced using multiplex PCR. This molecular testing confirmed vaccine-component genes in excised tissue, offering a definitive diagnostic method.
Area of Science:
- Immunology
- Pathology
- Molecular Biology
Background:
- Vaccination-induced granuloma is a recognized clinical condition.
- Comprehensive pathological and microbiological diagnostic methods are infrequently reported.
- Distinguishing granuloma from other conditions, like malignancy, can be challenging.
