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Published on: February 6, 2016
Preparation of CuInS2 Quantum Dots with Reduced Toxicity for Biological Applications
Letícia R C Cunha1, Cecília B da Silva1, Milene E M Castro2
1Grupo de Pesquisa em Química de Materiais, Departamento de Ciências Naturais, Universidade Federal de São João del-Rei, Campus Dom Bosco, Praça Dom Helvécio, 74, CEP: 36301-160, São João del-Rei, MG, Brazil.
Abstract:
This chapter describes the synthesis and characterization of copper indium sulfide CuInS2 (CIS) quantum dots (QDs), as well as their application in cellular labeling and cytotoxicity assessment. Specifically, the synthesis process was optimized to obtain QDs with desirable optical properties. The characterization is mainly based on X-ray diffraction (XRD) and spectroscopy techniques, such as absorption, emission, and time-resolved photoluminescence measurements. Additionally, cytotoxicity tests were performed to ensure its suitability for biological applications. Finally, cell labeling experiments were conducted to demonstrate the potential of CuInS2 QDs as efficient fluorescent probes for bioimaging.
