Related Experiment Video
Updated: Aug 8, 2026

07:49
Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
A Rare Case of Storage Mite Anaphylaxis in Infancy
1Department of Allergy and Immunology, Sydney Children's Hospital Randwick, Sydney, New South Wales, Australia.
The Medical Journal of Australia
|August 7, 2026
Summary
Storage mite anaphylaxis, a severe allergic reaction, is reported for the first time in Australia. This condition can be triggered by stored foods, necessitating prompt diagnosis and preventive measures.
Area of Science:
- Allergy and Immunology
- Pediatric Allergy
- Food Safety
Background:
- Anaphylaxis is a severe, life-threatening allergic reaction.
- Previously tolerated foods can unexpectedly trigger anaphylaxis.
- Storage mites are a potential, often overlooked, allergen source.
Purpose of the Study:
- To report the first case of storage mite-induced anaphylaxis in an Australian infant.
- To highlight the diagnostic challenges and clinical presentation of this condition.
- To emphasize the importance of clinician recognition and preventive strategies.
Main Methods:
- Case report of an infant experiencing recurrent severe anaphylaxis.
- Diagnostic evaluation included skin prick testing to foods and aeroallergens.
- Serum-specific IgE testing was performed to identify specific allergens.
- Clinical history focused on food storage duration and reaction timing.
Main Results:
- The infant experienced two severe anaphylactic episodes linked to stored foods.
- Standard food allergy tests were negative, but sensitization to house dust mite and storage mites was confirmed.
- The patient required multiple doses of intramuscular adrenaline for each episode.
- Skin prick testing indicated sensitization to house dust mite, with serum IgE confirming storage mite sensitization.
Conclusions:
- Storage mite sensitization should be considered in infants with unexplained anaphylaxis, especially after food storage.
- Early diagnosis and avoidance of storage mites are crucial for preventing recurrent, severe allergic reactions.
- Clinician awareness is essential for timely diagnosis and management of storage mite anaphylaxis.
Related Concept Videos
Allergic Reactions
Overview
Hypersensitivities
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Hypersensitivity Reactions: Immune-Complex Reactions
Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum sickness, a systemic...
Allergic Drug Reactions
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Antibody Structure
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...

