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Relapsing-Remitting Perimyocarditis and Emerging Acute Myeloid Leukemia

Madeline B Zipperer-Giblin1, John I Bowman2, Nidhi Patel3

  • 1Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, Florida, USA.

JACC. Case Reports
|August 7, 2026
PubMed
Abstract

Insights

Perimyocarditis, inflammation of the heart lining and muscle, can be an early sign of acute myeloid leukemia (AML). This rare presentation highlights the need for vigilance in diagnosing hematologic malignancies.

Area of Science:

  • Cardiology
  • Hematology
  • Oncology

Background:

  • Perimyocarditis as an initial manifestation of acute myeloid leukemia (AML) is exceptionally rare.
  • Fewer than five contemporary cases have been documented in medical literature.
Keywords:
acute heart failurecancercardiac magnetic resonancereduced ejection fraction

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