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An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
07:50

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

Published on: June 4, 2021

[Endovascular treatment of iliofemoral venous thrombosis]

Lærke Urbak1, Jørn Dalsgaard Nielsen2, Mikkel Taudorf3

  • 1Afdeling for Karkirurgi, Københavns Universitetshospital - Rigshospitalet.

Ugeskrift for Laeger
|August 7, 2026
PubMed

Endovenous procedures have been shown to offer an effective treatment for Iliofemoral deep venous thrombosis with a clinically relevant reduction in postthrombotic syndrome (PTS) compared to anticoagulation alone. Catheter-based thrombolysis reduces the risk of PTS but has been shown to cause periprocedural bleeding in about 3%. This review finds that mechanical thrombectomy has emerged as an ideal technique, with thrombus extraction without bleeding and a significant reduction in PTS at 12 months. A large randomised controlled trial including this technique versus anticoagulation is ongoing.

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