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Tooth Extraction Outcomes and Complications in Diabetic and Nondiabetic Individuals: A Systematic Review and
Anupam Singh1, Srikanth Gadicherla1, Kalyana C Pentapati2
1Department of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India, manipal.edu.
International Journal of Dentistry
|August 7, 2026
Summary
This systematic review found no significant difference in tooth extraction healing or complications between diabetics and non-diabetics. More high-quality research is needed to establish clear guidelines for diabetic patient dental care.
Area of Science:
- Oral Surgery
- Endocrinology
- Wound Healing Research
Background:
- Diabetes mellitus is linked to vascular and inflammatory changes impacting wound healing.
- The effect of diabetes on post-tooth extraction healing remains unclear.
- This review addresses the gap in understanding diabetes' influence on dental extraction outcomes.
Purpose of the Study:
- To systematically review and compare extraction socket healing and complications in diabetic versus non-diabetic patients.
- To evaluate the current scientific evidence regarding diabetes and tooth extraction outcomes.
Main Methods:
- A systematic literature search was conducted across PubMed, Scopus, EMBASE, and Dentistry and Oral Sciences Source.
- Five studies, totaling 500 diabetic and 364 control patients, were included after screening 821 results.
- Data extraction followed MOOSE guidelines for systematic reviews.
Main Results:
- Diabetic patients showed larger mean socket sizes at day 7 compared to controls.
- No significant differences were observed in delayed wound healing rates between groups.
- No statistical significance was found for complications such as dry socket, bony sequestra, or infection.
Conclusions:
- Current evidence does not strongly support that well-controlled diabetes leads to poorer healing or increased complications after dental extraction.
- There is a need for high-quality studies and evidence-based guidelines for managing diabetic patients undergoing dental procedures.
- Stage-wise recommendations are proposed to improve clinical management and address existing ambiguities.
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